I have not used the EC/SS with the HD650, but used to own the Eddie Current amp. It is my understanding that it is a dandy power supply for high current/low impedance cans such as Denons and especially Grados - it was made specifically for the RS-1 - and so worry that it will fare less-well with higher impedance models. As you may know, the HD650 is an 'amp-finicky' set of cans that will sound amazing on a very good rig, but also may show the deficiencies in a less-than complimentary one. It is ultimately up to your ears what you eventually think of the pairing, but, yeah... the HD650 is definitely a more fastidious pair of headphones than most, with relatively high impedance requirements. The comparable HD600 is much more forgiving on lower-impedance rigs, as best I recall.