It is always fun to look at comments in audio science / sound science forums. The comments are so "creative". Hmm... could I be Rob Watts? or the developer of HQPlayer? or an AI-driven BOT? Or someone else? I know the answer but I would keep it for myself.
Learning how / why people create pseudo science claims are my interest. In pseudo science, there are always something look factual mixed with somethings that are really factual. It is a good learning opportunity for me to learn about the factual stuffs; meanwhile, in the learning process, it often shows how good / bad the people are doing in attempting to use the factual stuffs to cover up somethings that look factual but indeed not.
Upsampled music is like a subset of Hi-Res music. If people believe that "
Hi-Res music is useless", they would believe that "Upsampling is useless" too.
But, is Hi-Res music indeed useless? We had a long discussion on this topic with a
closed thread. (FYI, that thread was deleted completely, i.e. no one could see it. But it re-surfaced magically after a day or two). Anyway, have a look of that thread and make the judgement yourself.
If you ask the question to one of the most advanced
objective AI engine, ChatGPT-4, you would get the following:

Based on the above reply, people who cannot perceive the difference between CD-quality and Hi-Res music (for whatever reasons) could save a bit on the HiFi equipment, disk spaces, and cost for acquiring Hi-Res music files.
I would suggest people to check if they can hear any difference by using high quality upsamplers (e.g. M-Scaler, or HQPlayer). This may probably help them to tell if they are lucky ones who can save some money. (I am not that lucky, LOL)
Having said that, we all know that AI may not be 100% correct all the time (even with GPT-4).
However, its answer could give us some insights about the question and where to look for more information.
Cheers,

(Sigh... I'd just spent some money to get a better DAC for playing my DSD256 music that is upsampled from CD-format...)