Personally Nope, but its defiantly a preference thing. I Do feel the vocals are a bit more "musical" on the 1000x, but on the 2000x they have the full extension of naturalness, Closer sounding to being inside the studio with them. At least for female vocals, for male vocal its to hard because the 1000x isn't the best with metal (cymbals) while the 2000x is smoother so i spent most of the time with the 2000x & male singers. The difference between the 2 is actually quite small, but when you explain the sound it makes it sound larger than it really is but that's basically the only real difference the 1000x is warmer & musical, while the 2000x is smoother & more detail, just a notch up in the detail e.g. full range of vocals from natural to nasal & you can even hear the full tone of the strings (quite literally) on guitars & bass guitars while the 1000x is more the guitar chord & bass note.