I've had grado sr225's, and plenty of other open or open-sounding headphones (A700's, 595's, etc.). I bought the Ultrasone HFI-780's a while back, but never really spent much time with them for whatever reason. Recently, however, I've started listening to them again in earnest and I've fallen in love with them.
They handle the lower end fantastically. Base extends nice and low, and gives you that rumbling feeling that you get from many dubstep tracks (listen to The Bug?). Unlike other headphones that I've tried, however, the presence of the base does not overwhelm or even distract from the mids and the highs. If you're interested in rock and dubstep, I'd definitely suggest holding out until you can afford the extra $40 and go for the 780's.