(WARNING: MILD SPOILERS AHEAD)
I saw the 10AM showing and I thought it was good for a Hollywood movie, but...
It sucks when you're a fan of a comic or book or whatever a movie is based on and the movie is so utterly unfaithful to that book.
Some of my quibbles, as a comic fan:
* organic webshooters -- the reason this sucks is because back in the day, Spidey (being a scientist and all) developed new formulas all the time, this was something that developed gradually and was the real symbolism of Peter's intelligent side
* chronology of events -- in the comics, Spidey didn't really "meet" MJ until a blind date, despite her being his next door neighbor as a kid.. at this point, she became Pete's fifth girlfriend, I think
* lack of comedy -- someone else said this one too, but if you were to summarize Spidey in a 5 minute film, you'd make him deliver a cheesy one liner... Spidey is practically where cheesy one liners originated but I gotta tell you, it's a very odd thing to have to complain about being missing in a Hollywood film -- I counted one oneliner in this film, just one
* MJ and Pete's relationship -- I don't want to spoil here, but I really don't like the way the movie handled this
* the spider that bit Peter lived -- obviously this is some ploy to create a villain in a sequel, but it annoys me
* Spidey and Green Goblin's relationship -- without spoiling too much, I didn't like the whole join me bit, too Biblical for me
* Pete & Uncle Ben -- I didn't like how Pete gets into an argument with Uncle Ben before he well, you know.. in the comic, it's Aunt May that got into an argument with him that day and (as recently revealed) is a reason May and Pete both share some guilt about that day
* Not enough interaction/character development of minor characters. I'm sure that was supposed to be Gwen and Robbie at the Bugle, but the audience didn't even get an introduction -- it felt like minor characters had been cut which caused...
* Pacing was too fast -- the entire movie flew by without any real chance for development, it moved scene to scene based only on action, not on content
* Pete became buff as soon as the Spider bit him--in the comic he remains a scrawny geek and slowly builds muscle mass over his years of climbing and swinging around New York
I liked a lot of other things, though--I liked the warehouse scene a lot. I loved the visual effects, though I have mixed feelings about the 3Dness of his costume. The characterization for the characters there weren't bad. The dialog was, for the most part, great. And although Kirsten may not be a super model, the acting for all of the characters was at least acceptable, so the opportunity cost there was probably worth it.
*shrug* It could have been better but it certainly could have been worse. Maybe I'd be less critical if I hadn't been waiting for 13 years for it.