I own the U10 and went through some girations to get the sound the way I wanted it. First, I went with the JVC Spiral Dots for the tips. Better seal and response IMO than the Comply, Spin Fit, or others I tried, although they don't fit snugly on the IEM. Then I ordered the UE Buffer Jack that introduces 20 OHM of resistance and suddenly the sound was exactly what I was looking for. I like solid bass, strong mids and articulate highs. My ideal IEM, in a word, would be described as "resolving". However, I am sensitive to a headphone with prominent highs (see HD 800) and am definitely not a bass head.
I think the U10 provides a nice balanced palette to begin with. They just need some simple tweaks, IMO.