I use the Focusrite 2i2 interface and Rokit 8 G3 powered monitors. The detail and separation on well recorded lossless files is astounding...to me anyway. The only thing I think might have better DAC with balanced outs is the Xonar One but I haven't tried it..yet lol.

I use Focusrite 2i2 USB audio interface to  KRK Rokit 8 G3 monitor speakers on balanced connection. No noise. 

you think I be making a mistake with a less expensive Focusrite Scarlet 2i2? http://global.focusrite.com/usb-audio-interfaces/scarlett-2i2/specifications

What computer interface are you guys using with your pro monitors? I have Rokit 6 , Rokit 10S subwoofer. I would also like to use it as a headphone amp for my 650's.