If that's of any use: it happened both using PureMusic as well as BitPerfect. (And of course direct from iTunes too)

Hi Jason, I didn't even know it was a known problem until now    I can confirm that I've had it happen to me a number of times on both the Bifrost + Lyr and again with the Gungnir + Mjolnir. Switching from USB to another input and back clears the noise problem immediately. It's exactly the...