I was hesitant buying these closed cans. I've read everything from floaty bass to decimated vocals. However I've learned that you can only believe what you experience yourself.
I was also bit hesitant with these cans because their frequency response curve was a bit amped over my baseline AKG K701 / Sennheiser HD598. However, I wanted to find a closed can that was close to the HD598 with a bit accentuated bottom end. What you'll find is these cans have an odd signature in the curve.
What I found is these cans produce a large clean sound. The bottom is punchy, but not muddled however you may find at louder volumes you may want to moderate how much you use these cans as they can be quite bottom end responsive. Be aware there is a PRO and a CONSUMER variant with these headphones. Black are the PROS and grey is the CONSUMER. The Pros have a bass port to allow the diaphragm breathe.
However! This bottom end doesn't come at the expense of losing the mid and highs. In fact, I found that the high end was nicely smoothed so you shouldn't find much shrill with these.
What I really enjoyed with these headphones is they were very adaptable to a wide range of genres.
The headphones are light, well constructed and very comfortable. BUT... not necessarily those with endowed ears. Beyerdynamic chooses to use a circular design versus a oval like Sennhesier so those with large ears like me may find a break is needed to ease the long periods of listening since you can get a bit of ear pinch. I found though the band clamping is not excessive.
Last thing on the headband, that as it springs open it clamps the earphones so to adjust it's best to allow the headphones to close. I think this is a design that carries through the DT series of headphones (880, 990).
Driving these phones I used cMoyBB and I was surprised that my iPhone 3GS worked fine as well. However I would recommend you amp these cans to properly drive them since you want to take advantage of the higher resistance of the 250 Ohms (there are 32 and 80 Ohm versions available).
Bottomline:
If you want a closed can, you will be hard pressed to find a better sounding set of headphones that are cheaper.