You can open the blades on Leatherman Wave, Surge and a few other of their multitools one handed. One reason why I love it so much. All you need is your thumb to open them.
I think I'll be taking a nice, dedicated pocketknife as well as a leatherman for random stuff...
So far, I think I'm going to go with the Vapor. I definitely want the assisted opening, so I can use it one-handed, and I don't need/want the waving because I probably won't need it or use it ever.