Currently using an ipod classic with apple lossless and ortofon e-q7 iems.   This is primarily used at work while sitting at my desk.   I'm looking for a DAC, amp, and possibly a dock if required.   These don't have to be portable.  An all in one unit would be nice due to the lack of...

One of the main differences is that I "feel" the music with speakers.  Also the imaging and other things you mentioned are so much better than any headphone I've ever heard. I can close my eyes and point out where each voice or instrument is located.  There's a LOT more depth with a quality set...