If the channel imbalance has occurred recently but didn't exist earlier it
could be the tube if there has been a significant drop in emission in one of the triodes. Only way to know that for sure is to test the tube.
I don't know what TubeDepot is referring to with the high gain option. If they are simply selecting tubes with higher GM or emissions (relative to other like tubes), then it isn't going to make one iota of difference in the sound and is, quite frankly, a pile of marketing BS. Perhaps there is something else they are referring to, but I'd love to know what it is. The important thing with the Vali 2 is to have good GM balance between the triodes, and I wouldn't pay extra for anything beyond that.
In my opinion the EH 6922 isn't a very good sounding tube to begin with, so almost anything you replace it with will sound better.
The TungSol 6SN7 will require an adapter (and probably a socket saver) if you're willing to do that, otherwise there are lots of alternatives in the 6922/6DJ8 family that can sound very good.