40
Might be the production run number.
280
I think this is the batch number
63-40
This is the Date code. The tube was manufactured in the 40th week of 1963
JAN-CRP-5751
JAN is short for Joint Army Navy. These tubes were manufactured for the US military. As such they had to be especially rugged and have very high quality control. That does not mean they automatically will sound superior, just that they are well made tubes.
1) What does JAN mean?
See above
2) Why are NOS tubes so much more desirable/better?
They last a long time in actual use. Many NOS tubes have a unique sound that is highly sough after.
3) Assuming the answer to 2 is that they were made better and are better quality during the "tube era", why does no one make good tubes anymore?
There are some good sounding tubes made today in the former Soviet Union (Sovtek, Electo Harmonix premium brand). They may not last as long as a NOS tube because the vacuum inside the tube is not as good, they don't take the time to pump out all of the air that would make a longer lasting tube.
4) What happens when the supply of NOS tubes runs out (I know that will take a loooong time, but it's interesting to think about)?
As long as their are electric guitars there will be a demand for tubes for tube guitar amplifiers. The more common small tubes such as 12AX7, 12AU7, 5751 will continue to be made, the less common ones will become increasingly rare until the price of a single tube makes it impractical for the average person to restore a vintage piece. In the case of output tubes, when the supply runs out, if there is a similar replacement tube being made then people will have the option of changing the tube sockets on their amplifiers to use the substitutes that are still available. One example, the 7868 tube used in some amplifiers including the Fisher 400 receiver is no longer made. The 7591 tube is an equivalent tube with a different base and pin configuration. If you replace the tube sockets in the Fisher 400 with tube sockets for 7591 tubes and rewire for this tube, you can use the 7591 in the Fisher. (It might be a tight fit as they 7591 are a bit fatter due to the base structure of the tube.)