I've grown to prefer the comfort of customs. Universals can also be comfortable but it's very hit and miss depending on the design of the earphone, what tips it will fit etc... The universal Roxanne will likely possess a larger than average housing and that could make it difficult to for those of us without huge (Mickey Mouse style) ears. I'll hold off until a few of these are out in the wild before I seriously consider my options.
Why would the Universal Roxanne be larger than the Custom version? If you've seen many customs, they're mostly empty space, in order to fill up a person's ear.
The Universal version is no longer constrained to the size of a person's ear and can be made as small as possible, containing just the drivers and components. If the Universal Roxanne's housing is too large for someone, there's little chance the Custom will fit either.