The isoregen or other isolation devices indeed can interfere with the SQ. I took out my ifi products as they just change the sound eg warmthen it and degrades the clarity/sound stage. They only work well for a week source.
TOTALLY AGREED!!! So many people use multiple reclockers- and in my experience it usually damages. My last DAC before I changed over to audio-gd only had coax input; no USB so I used a Shiit Audio Eiter USB to SPDIF converter with built in rechecking. It cost around $100. When I placed the world famous SOTM tx-USB ultra special edition reclocker in front of it with a world class power supply, - the sound changed- but not necessarily for the better. It was a lateral move; a bit smoother and fuller but less crisp. The Regen ISO before the Shiit Eiter really damaged the sound.
Be careful with multiple reclockers. The only device I have found to help under all conditions before every reclocker I have ever had is a "jitterbug"; maybe because it is passive and has no power supply.
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