I dunno about the Titanium HD, but the GSX1000 doesn't have a very powerful amp. However, it does have an awesome virtual surround in GSX. As far as your headphones, considerable upgrade from two excellent headphones for gaming purposes? Not particularly. If you want improvements on technicalities, sure, but if the main goal is gaming and detail retrieval, there's no real point spending so much just for that purpose. I'd make an assumption in that maybe something like the HD800 would be a meaningful upgrade, and you ain't gonna be driving that with a GSX1000, lol. The goal in upgrading from something like the 598 would be for more musicality and enjoyment, and less for brute forcing clarity for gaming.