I remember when I upgraded to Burson V5i opamps on the X7 and had really bad cables and pops. I thought it was the opamps, but it was the USB cable. Swapped it oht for some no name, and it sounded perfectly fine. I'm not someone to preach about usb cables, but I would at the very least say to find a cable known to do well for audio duties. That and yes every usb port on your pc. I have noisy ports in all but like one or two ports.