Yes, I enjoy my Uptone ISO Regen. It's provides a subtle change but its by no means a "must have". I guess my broader point is that Jitterbug ---> Eiter --> Singxer --> Holo seems a bit redundant. If you get your Singxer / Holo you can experiment with removing/introducing components in your USB chain to see if it really makes a difference. I spent a lot of time trying components in front of the Singxer and gauging their audible benefit.