Your ears are highly developed to detect those nuances.There is definitely a problem in the high mids. The violon and horns sound nasal. My ears are tired after half an hour of listening to this interface even at low volumes. I don't have that sensation when I use my Apogee Duet 2 or plug my CD player directly in the amp.
Crazy amounts of details & wide sound stage doesn't compensate the tiring sound.
(I've used USB, Toslink & Coaxial for my tests.)
I didn't sense those things when I used only USB input.
My unit (very early production) has some sound delay with USB input.
It's quite annoying...
With Toslink & Coaxial input there is no delay of sound?