I'm a Lame 320 CBR guy, and I have yet to find any file that I can ABX that identifies a problem with the encoding. I use this format because it works on every device and Google Music does not mess with it when I upload it. I'm at the point where I stopped worrying about those glitches in a song, because I hear it on YouTube, I hear it in MOG, I hear it in Spotify, I hear it in Pandora, I hear it in Sony Music, and if I also have the CD, I hear it there too. I'm confident that Lame 320 kbps CBR is transparent to my ears and equipment. I have not even seen any proof that anyone can tell a difference, but I know that I cannot.