I dislike conventional earbuds alot, and I own Etymotic ER-6s. I have to say that the Etys really do not bother me when I'm just listening. Trying to do some things (chewing!) is a whole another story. They are not as comfortable as say a full sized pair of cans but they are certainly tolerable. If you order from Headroom you can try them out for 30 days. Worst case is that you don't like them and are out shipping costs.
Another thing you have to consider with almost all in-ear phones is the isolation. Not one to exaggerate, if I have my Etys in with my music at a reasonably loud volume I wouldn't be able to tell if somebody was screaming two feet behind me. Maybe this is good, but if your planning to use these while riding a bike or traveling along city streets I would get something else. I also have to warn you against buying these for jogging or exercising. Although some people say that the ER-6s have low enough microphonics for these activities, I find it extremely annoying, even if I am only walking to the next room.
That said, they are outstanding sonically; based on my (very limited) audio experience, they are by far the most detailed and neutral headphones/speakers that I have heard. I find the isolation to be very handy, especially for that 14 car ride with the family or for the 20 hour flight with the screaming baby sitting in the seat behind you.
In-ear phones certainly aren't for everyone but I would give them a shot if you are considering new headphones are need something for traveling.