Most of the time when I'm at home I listen to my HD600s, purely for comfort reasons. It's simply for enjoyable sitting in front of a computer or in an armchair with those things on than my etys.
In bed at night, I listen to the etys, but only because I can't be bothered moving equipment around.
Actually, there's another reason as well -- I don't like my etys through my amp. They are the er4p, so maybe that's why, but I actually think they sound better straight from an MD than they do through my home rig. Call me crazy...
And I can't be arsed spending AU$100 plus shipping for a conversion cable when I already have great sound through the Senns.
I love my etys with all my heart, and I won't fault their sound, practicality, or comfort now that I have become accustomed to them. But the bald faced truth is that they will never be as comfortable or practical for home use as the HD600, when you can hear the phone, other people, etc. I live by myself, so there's nobody else around to hear someone knocking on the door, for instance.