Im about to graduate.
dont do drugs
dont drink often or in large quantities
date nice women who care about you and encourage you
keep in touch with your family
study daily, even if only for a few minutes just to keep yourself continually focused on your main goals and reasons for attending college.
Get plenty of SLEEP!! Nothing can possibly compare with this. If you get sleep you will come out of college feeling ready to take on the world. If you habitually stay up late and **** your circadian rythm up you will graduate from college feeling burned out already.
Make sure you are going to college for you own reasons and not for anyone elses. Intrinsic vs. Extrinsic motivation. You will be happier if the reasons that motivate you are intrinsic. Don't choose your major based on peer pressure, social pressure, or because you wan't to be rich. It's difficult and it seems obvious, but you should really make sure you are clear on this.
Stay in the dorms the first year, or maybe the first 2 years. It's just easier, trust me.
Have fun, but have good clean fun. Being irresponsible is great just as long as you aren't ****ing yourself up. I knew a couple kids who turned into alcoholics in college, they weren't close friends of mine but I still saw it happen.
Alcohol inhibits your brains ability to heal itself. Whenever you drink and your "having fun" remember that you are doing so at a cost to your body. So don't confuse fun with stupid.