If you REALLY want to hear some major improvements, mainly in the form of dynamic range and size of soundstage, as well as cleaner smoothly detailed sound with less distortion, substitute the 12AU7 with a 12BH7(a).
It should drop in no problem. Not an EXACT replacement, but a very, very commonly used one.
For the very, very best try the Tung Sol 12BH7A oval black plate. Also in the same league is the Raytheon 12BH7A black plate, and Westinghouse 12BH7A black 'wing' plate. Sylvania black plates are good, too. Another one that is in the same ballpark, and might even be the best of them all, is the early 1950's CBS-Hytron 12BH7 black plate.
As far as others go, the RCA black plates are okay. A good tube. But I prefer the Tung Sol and CBS-Hytron.
Another I have had the chance to own, but did not give enough evaluation time, is the BRIMAR 12BH7 black plate. One of the few European entries of 12BH7 type. If you can find one, I imagine it has it own unique sound. Very often re-sold as GE, but is a Brimar.
As far as 12AU7 go.... a MUST TRY is the very, very hard to find, but when found very reasonably priced EARLY version of the RFT min-plate ECC82. The one you want is from the late 50's early 60's, and is distinguished by the getter... it will have a FOIL or solid getter, and a comparatively uneven getter flashing. This tube is to DIE FOR. Now, be careful, the later RFT with O-getter doesn't cut it in quite the same way.