Will the E10 actually provide a noticeable difference compared to the direct connection before? 

Ok so I have grado sr80i, v-moda crossfades, as well as superlux hd668b and I am looking for a dac/amp that can just sit on my desk so portability is not an issue. I have a macbook and I am still not quite sure how all of the connections work. I listen to alternative, folk, and rock music...