Originally Posted by Mshenay
no no, just kidding, others have mentioned some nice stuff for it, although I would think [it might work as a some what jerry rigged player] but does Apple not have a some what High End Video or Music editing software, that might double as a rather nice high quality playback software, that won't prompt with any of iTunes usual foolishness
Not really… As a long time FCP editor and hobbyist with Logic, both are suited for what they actually do, and would be really rather unpleasant to jury-rig into media players. At that point you're better off going for Decibel, or Audirvana, or Fidelia, or jRiver, or… There are plenty of alternative solutions to go around, but it is perfectly doable without leaving iTunes, if one wishes.
Originally Posted by headdict
For non-critical listening you can as well use iTunes without the hassle or extra apps needed for bit-perfect playback. In this case it will resample according to your Audio MIDI Setup settings. Not necessarily a bad thing IMO.
This is very true, and brings up one other notable point… While using a mismatched sample rate (be it higher or lower) will always result in resampling, one can safely leave the output at 24 bits regardless of the original depth… it (essentially) just gets padded with nothingness.