But more seriously, have a look at Rocky Mountain Audio Fest videos of presentations by people like Keith Johnson, and think about how he takes a much more (literally) "outside the box" view of common problems with audio systems, focusing on system-wide interactions. Or consider the age-old argument about whether power cords matter. You can look at the power cord alone and be stuck in the same old back-and-forth: "But I hear a difference!" "But you can't from 3 feet of wire!" Or you can look at it from a system perspective and with a couple of bucks worth of parts you can make your transformer much less subject to "ringing" behavior and thus tremendously reduce or eliminate any sonic difference from power cords. (Google "snubber circuit," "Hagerman," and "John Swenson.")
Ok, I get where you're coming from now with the comment. I was having trouble understanding the context. I totally agree that a whole-system approach to design will always give better results. As a chemical engineer, I've seen a lot of systems fall apart because one part of the system was designed separately and does not "talk" to the rest of the system. PID loops are single in-single out as well, so that causes a lot of horrible problems since people are too cheap to implement more elaborate control schemes.