hmmm I was about to recommend the KEF M500 for comfort, isolation, and sq until you said full-size is preferable.
Other than that, the Beyerdyanamic T70p and the AKG K550 sound amazing, almost like open headphones.
I've heard a lot of good things about the KEF M500, but I've never enjoyed on-ear headphones for more than an hour or so.
That's just my personal taste :)
that makes sense. By the way, what are your genre preferences?
I enjoy tons of different music; mostly jazz, but also electronic music and soundtracks (classical).
Over time the headphones I've enjoyed most were ones with a strong(er) bass - but not overdone like the Beats.
ok then, forget the Beyerdynamic and the AKGs. Go for the Momentums or the MDR-1 or the V-Moda or the P7s. Which is exactly where you started from. Sorry for being no help :)
Hehe... no worries
Getting a new pair of headphones is just as much about deselection as selection.