I guess when I started this thread I was in a lossless-denial phase due to the convenience of Spotify Premium. But after a while, I have to say that now I must concede to the fact that 'good enough' is never actually 'good enough'.
I'm not gonna say I can clearly tell the difference of lossless files (I'm using WAV) to 320kbps MP3s, but over time I noticed when I listen to WAV files I drift away into the music much faster than MP3. It takes longer for me to 'drift away and enter' the music with MP3 or Spotify, sometimes I may not 'enter' the music at all. I'm not claiming that I can hear apparent audible difference, but simply put I feel like Spotify is very mechanical and not as smooth compared to WAV / FLAC.
Perhaps this is what new audiophiles experience when upgrading their file source? At least, this is what I encountered. I guess again, thank you Head-Fi for the ruthlessly impeccable support of emptying my wallet