There has been substantial poof that the 8 wire square knot lacks the neutrality of the 16 wire octoknot. All has to do with flow. Just as the garden hose speaker cable lack the flow, realism and neutrality of the fire hose speaker cable. Even if using a 1.8 TRS connectors, nothing beats a 16 wire octoknot cable...except a 32 wire hexaflourocarbon cable.
And, yet, none of that matters if you don't have your audiophile grade acoustic stones and hangers.