I looked at one in Guitar Center yesterday...unfortunately I couldn't listen to it, LOL!
What I can say is that the build quality is outstanding, far exceeding the 0404 USB which I've been using for 6 years now. The UR22 has some heft to it, and while the pot knobs are small, the overall feel is top notch, just like high end studio gear. No one would use the phrase "like high end studio gear" when describing the 0404 USB.
One of the reasons I liked the 0404 USB at the time was that the proprietary drivers seemed to perform much better than standard USB Audio on XP, but I suppose that's no longer a big issue. I was about ready to buy one just to listen but have better things to spend hobby money on right now.
Edited by sejarzo - 1/31/13 at 1:36pm