I've owned the hd218's, same design as the hd228 basically. I wear glasses, and they definitely do not interfere, there's a small gap between your head and the headband.
Very comfortable, very light, no extreme clamp like the ath-m50's, i can only get about 2 hours on those then it starts hurting.
Sadly with the hd218's they have slightly less noise isolation than over-ears, essentially a home-use option only, they will still block out sound.
You also have to get your ear exactly on the holes in the pads, otherwise you don't get the full sound.
Bass is what the hd218's specialises in, punchy, plentiful, not bloated or woolly. Mine might have been the bass version though, i don't quite recall.
With mids, vocals are very close and personal, as if the person singing is next to you. The amount of mids, i feel, is equal to the amount of bass.
The treble extension isn't spectacular, that's the only downside of the hd218's, the lows and mids overshadow the highs.
They don't have much sound-stage though, they sounded quite closed in and personal. Might suit nightly movie watching.
In-ears are not comfortable for gaming, for me anyway.
Edited by ThatNzGuy - 1/7/13 at 8:59pm