I'm personally excited about the soon-to-be released Bioshock Infinite in early 2013. Pre-order now and we can get a DLC called "Industrial Revolution," which is supposedly a puzzle game with tie-ins to the setting of BI. The two previous Bioshock games were some of the most original and thought-provoking games I've played, and I have very high expectations for this one too.
Dunno if you saw the posts I made a week or two ago, but I was talking about BioShock Infinite quite a bit and linked to some awesome videos of gameplay footage. I'm a massive BioShock fan.