Well I have had my HE-400's well over a week with the Lyr and have put MANY hours on them. I have to say these have really grown on me. I have gotten full used tot he sound now and really enjoy it. I have been comparing these to my Denon D5000 and have to say they may be slightly better to me. The D5000 have a lot of bass but its not as clear and seems boomy to me compared to the HE-400. Tough comparison as one is open and the other is closed but I am surprised how nice the HE-400 sounds. The treble is still kinda "piercing" to me but can easily eq'd (except when listening to MOG streaming, cant find a way to eq that). The Lyr seemed to smooth the treble out for me though a bit. I also have the D5000's on a Schiit Asgard and they sound very nice.
All in all I love these head phones and am now very happy with the purchase.