The markup is no doubt high, but even in the $300-ish price range I think their price is totally justified... As long as you know what you're getting. They're kind of bad for most genres, and so if you're buying them just to try them or something, you'd probably be pretty shocked by how they sound for most genres.
They're so, so delicious for folk, and other vocal-focus genres, though. There's a caveat there, too, I found out. I recently had a chance to try these out of my friend's Shiit Lyr, and they didn't sound nearly like they do out of my Little Dot I+. The mids set back a bit, and the ridiculous micro detail that I get on my setup completely disappeared. I think these need a transparent or solid state amp.
I think Dyaems mentioned these respond well to different amping, a while ago, but I couldn't test that claim. I find it to be true, now.