I've had these for a weekend, and really, they are pretty much the perfect portable headphones for me. Without EQ they do good for a fair amount of my music. For rock, jazz and classical though, in most case (not all), I need to lower the bass and increase the treble ever so slightly. This makes those genres far more palatable on these phones.
As for comfort, they are more comfortable than my TMA-1s, which is good. Basically my comfort goes as thus. No issues, some pressure on my ears, then after my ears get used to that (numbing?) they are perfectly comfortable again. It is a weird roller coaster, fortunately the discomfort only occurs after around 1:45 of wearing. For home use though, which I plan to do a lot with the boom mic, I extended wear is fine.
I would like to try the XL pads though.
To note, I only have 10h of Pink Noise burn in. I usually do 50... so we'll see how that goes.