Why the preference for the HD 650? Have you heard them?
They are dramatically different from anything else you've mentioned, or that has been mentioned for you (except the HD 600) - they will very likely sound "bass light" or "dead" coming from the Beats or Bose QC headphones. The Denon AH-D2000 or AH-D5000 will be more of an "in-between" - you will get more detail, but retain the powerful bass impact and other "v-curve" attributes associated with most mainstream products. Regarding the Beats Pro, I haven't spent extensive time with them, but from what I have seen (I have had them on my 'noggin) - they are not as well put together as the images/materials would imply, and the sound does not fully justify the $400-some-odd price (although this is based on a very brief audition). They are much smaller in person than you might expect. They were not incredibly comfortable.
You can probably try the Bose and Monster products if you live near an Apple or Best Buy store; they often have demonstration sets.
Regarding amplification for the HD 650, they do not require substantial power in order to perform, but they do require a driver that can deal with their impedance. Lots and lots of cheap/mainstream components will not deliver this (I know that the Walkman NWZ-A series can, I suspect that many desktop audio cards can, but beyond that it's up in the air - low-end roll-off is likely going to be the biggest issue). I would NEVER consider them for any form of mobile or work use - they provide no isolation, and will not only leak sound to everyone around you (which is annoying for everyone else), but you will hear everything else around you (and if you crank them up to "block" the noise, you'll damage your hearing over time). I would consider something else - the Denon AH-D2000 is not a bad suggestion. I've read good things about the Audio-Technica ATH-A900 as well, but have never heard them. Both of these are closed, and both of them include a native 1/8" jack to plug into your portable. The Denons can play very nice with mobile devices.
Quote:
Originally Posted by
Frequen C 
Would the FiiiO E11 drive the HD 650's well? I would prefer to get the HD 650's over any other headphone.