It may not work sometimes. But rarely.
A hub can be passive or active. If the DAC draws too much power(maybe battery charge feature is on). It may not work with a passive hub(one that doesn't use external power) if it draws too much and other active devices are connected to that hub.
But yes. USB 3.0 is backwards compatable with USB 2.0.
Every 3.0 hub I've looked at has an external power supply, so it sounds like I'd be good.