I actually just posted a thread in the Lyr tube rolling thread. I'm also using the LCD-2.2 with the Lyr and stock GE tubes. My comment was that the treble was a bit abrasive. I'm not sure if this is a fault of the tubes or the solid state amplifier stage itself. I'm hoping that better tubes can fix this, or I may have to look at upgrading the amp.
The stock GE tubes are a little aggressive on the high end and a tad grainy. I don't think it's a bad sound at all, but it can definitely be changed with a set of good tubes. I have Amperex orange globe A-frames and they're very smooth and warm without any upper end harshness. There are some other moderately priced choices that are also reputed to be smoother. I did notice that the GE tubes mellow out with some use, but only to a point. It shouldn't be that difficult to smooth out the Lyr with the LCD2.2.