I tried my combo DAC 19-DSP + Audio-GD C2 (with OPA Moon when i made the test) with a Grado RS-1 (not mine), first i made a try with ACSS the result was satisfying : Big Bass well controlled, C-2 has good "grip" on it, medium was extremely pleasant, detailed and smooth and slightly colored (on some cans medium tend to sound too "metallic" or "woody", on the RS-1 it was just perfect), highs were smooth and extended but with a bit more "crunch" than all other Headphones i tried, but it was the first time i was listening a Grado...
My friend (the owner of the Grado) put it on his head and tell me that the sound was very good (he use to listen the RS-1 on his rig : Cambridge Dac Magic + Head-Amp Ray Samuels Audio HR-2), and then we tried both with the Moon OPA, i find the sound different but not better IMO : with the Moons the bass was more "chesty" and gave a better sensation of deepness but was also a bit more "boomy", the medium was slightly more colored and the highs sound more "rounded" (soundstage seems also a bit wider).
My friend preferred the sound with OPA Moon and tell me it was excellent, and I tend to prefer with ACSS because i found it more accurate...
The test was done on the track "So what" from the Album "A Kind of blue" and some various other pop/rock songs.
The end of the story was : two days ago, i bought a Grado :)