My Spud use two NOS $5 6CL6 TV tubes and one NOS $10 6CA4 rectifier...and sounds amazing...
This amp drives most cans and efficient speakers and can be built for well under $500!
Warning: Spoiler! (Click to show)
It is definitely possible but the designer has to 1) know what he's doing and 2) enjoy the process of trial and error to tweak for the best possible results as the tweaks just haven't been done yet for these odd ball tubes.
That looks nice. Here's to having some fun.