With so many threads about how sluggish iTunes is, and with all the things foobar2000 can do, seems that some people still use iTunes mainly because of iPod/iPhone sync.
Well, that's no longer a reason as there is a foobar plugin that does the syncing among other things. The plugin supports basically all iPod, iPhone and iPad devices out there
Check it here: http://yuo.be/wiki/dop:start
foobar has two VST wrappers available, which do work with a number of VSTs available out there, and DXi can also be used through chainers.
Regarding the controversial debate of resampling, for those who do use resamplers, don't use the default PPHS as it is made with cpu power savings in mind, not maintaining SQ. SoX resampler does a much better job. It can be found here: http://www.hydrogenaudio.org/forums/index.php?showtopic=67373
In case people don't like the minimalistic/bland look of foobar, you can apply skins that do enable added features besides a UI refresh.
Skins can be found here:
Just be careful not to apply a skin made for an older SDK of foobar, namely versions prior to 1.x
There's even the additional eye candy of being able to use a wrapper for Milkdrop, a well known and much liked Winamp plugin, which can be contained inside foobar's folder, without external dependencies. Both the visualization plugin and Milkdrop packages are found here: http://www.hydrogenaudio.org/forums/index.php?showtopic=59388
The only thing I find that foobar somewhat lacks, is a proper library management, but that's where MediaMonkey comes in, effectively replacing iTunes entirely.