It has an RCA out (for audio), USB (for power, PS3 or PC chat), and controller input (for 360 chat).
It has a standard 3.5mm input for headphones, so any headphone can be used, though if you want a non-Slyr or Astro mic, you may wanna have a female Y cable, like those Astro sells.
My assumption on hooking it up, basically just getting an RCA female to 3.5mm male to hook up to your own dolby processors. I don't have one, so I can't use the Mixer with my Mixamp (pointless, but it does allow me to use the Mixer's EQ to test out). For stereo gamers, you just plug in the console's RCA cables into the piggyback on the Slyr's Mixer cable. Not 100% sure how the piggyback cables work exactly. I did get sound by hooking up the PS3's composite cables directly to the piggybacks and leaving the male ends alone.
Edited by Mad Lust Envy - 12/15/12 at 10:27am