Yeah I spent ages reading up about nearfield monitors for my computer set up (as I spend most of my time in front of a screen rather than sat in a chair with my feet up) and under my budget, which would be around <£1000, everything I read always seemed to keep coming back to the Focals as they were generally praised for being accurate, musical and non-fatiguing if used as a desktop hifi speaker rather than for home production.
I got to audition the 40's, 50's and Twins the other week in a basement studio, just to see if they'd live up to the hype. I thought they were fantastic and left me sure that I wouldn't feel like I was missing out on bass response, despite listening to several genres of music where deep bass is prevalent. The Twins, like the 65s are too big for my desk (I physically can't put them on stands either side of it either), they're enormous, however fantastic they sounded - as they should for around £1000 per speaker in the Twins case - but the gap between them and the CMS50s wasn't so great I'd feel like I was missing out greatly. Hearing the 40s next to the 50's however, the obvious difference in low end was enough that I felt I had to get the 50s. I'm sure the 65's would be better still in this regard, but I can only work with the space I've currently got. In a bigger space with more room however, I'd definitely consider a future upgrade to the Twins, although I'm sure at that price range there's probably a lot of competition as well.
The other thing I liked about the Focals was they're designed and made in France, so it's not like they have to travel far if there's any problems. You don't read too much about them here, but I think that's more down to the currency conversion making them quite expensive for US customers, lack of availability compared to things like KRKs e.t.c. (although the Apple Store stocks them). I'd thoroughly recommend anyone looking for desktop speakers to consider them, as they're designed for non-optimum rooms/placement - which is what most of our desks and rooms are - and they seemed to hit all the right boxes in terms of sounding very enjoyable yet accurate and unforgiving. Viva la Focal!