Sorry to bump this up, but I have the same problem. I have Windows Ultimate x64, and its not working for me. I was using onboard sound with a optical cable to the emu for a while. But I want to start recording again, so I need the usb. I install the drivers, and it seems to work fine, but then I reboot and it doesnt see the Emu. Anyone know the reason for this and/or how to fix it/?