As nc8000 says, you will need to use a balanced to single-ended adaptor to use the balanced cable on a single-ended amp.
Many of our customers have gone this way, as they have a single-ended amp at the present moment, but plan to go balanced down the road.
We sell an adaptor with Neutrik jacks for $99.
Evey time you introduce a new component into the signal path, in theory, there is potential for some degradation of the signal, no matter how teeny tiny and potentially imperceptible. If you can avoid adaptors or headphone extension cables, theoretically you are better off. The Jena wire is very high quality and the Neutrik jacks are very transparent, so any potential loss is going to be extremely minimal to the point of inaudibility on all but the best associated equipment.