probably depends on how you define "audiophile"....
for the "audiophile" who believes that nothing sounds as good as vinyl, can tell the difference between power cords, transports, can "hear" differences that aren't measurable, etc. etc., probably not...
for the "audiophile" who listens to music because he/she enjoys it and doesn't obsess over every little thing that "might conceivably" (no matter how unlikely) interfere with their sound quality, the computer is REAL good...