There might be a bit of hiss on the TPA6120a2 Digital Volume amplifier.
I myself have noticed it.
I think it has something to do with the extreme speed and level of gain this chip has.
Controlling this chip is like controlling a nuclear reaction.
And I'm being quite serious.
The chip is so fast and responsive that it took allot of engineering just to get it stable.
At first the chip wanted to oscillate all the time and I suspect that is why you don't see too many amps using it.
It is just so hard to contain and control.
Now as to where the 'hiss' is coming from, I have yet to determine.
It may be that the chip is so sensitive it is picking up the noise of the resistors in the feedback loop...
Every amplifier has this type of feedback resistance but very few are capable of a 1300 V/μs Slew Rate!
Yes that's not an error.
It is capable of 1300 V/μs Slew Rate.
Try to find an op-amp or any amp for that matter that can do that.
And that makes that chip EXTREMEMLY HARD to master.
It could be picking up hiss from the source as well.
It is just very, very sensitive.
But to get performance like what it achieves, you have to have that kind of sensitivity.
Really, check out these specs:
http://focus.ti.com/lit/ds/symlink/tpa6120a2.pdf
Look at those numbers and try to find a chip that compares to that in any way.
If you find one let me know.
Keep in mind this hiss is very subtle and at the low end of the spectrum, like a low end pink noise, maybe coming from the universe....
EDIT: Just for the hell of it, I wanted to see if the models I have around here had "the hiss".
I had to first move to a very quiet room, that in itself was hard to find as there are fans and motors running all over this house... It is winter here after all...
After finding a reasonably quiet place, I just listened with nothing pluged in and I could not hear anything. Then I plugged in a 12 inch 3.5mm patch cord with the end open, and I could hear a slight, and I'm talking slight hiss, but I had to listen very hard to hear it.
Now to do a real test of this amplifiers internal noise, the input has to be shorted out and shorted out as close to the input as possible to create a "NULL".
I haven't done that, but I really see no need as with the cord simply unplugged I can't hear anything, so "NULLING" that would just be a waist of time for me. But I will build a "NULL" plug and try it one night when there is complete silence, perhaps camping in the woods on a freakishly quite night 
But back to reality, you have to test for internal noise with a DEAD SHORT on the input. That is the only real way to see how much noise, if any an amplifier has.
Else it could be getting noise from a number of places, sources, cables, etc.
And it has to be a damn good "NULL", Gold plated and Super High Quality. Some metals create conduction noise, Gold is the quietest.
This amplifier is that sensitive...
hotaudio40