Pros: Relatively neutral, extended bass, great with all genres, comfortable, detailed
I have the DT-880 Pro (250 Ohm) model and also own and regularly listen to a Hifiman HE-400, Sennheiser HD600, Beyerdynamic DT770 Pro (80 Ohm), V-MODA M-80, and others.
The DT-880 is really the only one that I find to excel at all genres from rap to classical and everything in between. None of the others have this much bass extension and impact, detailed highs that sparkle (a little bit sibilant though), and an overall neutral sound signature. For that reason, and because they are lighter and more comfortable than the HE-400, the DT880 are my most-used headphones.
Compared to the Sennheiser HD600, the DT880:
-Have better sub-bass extension
-Are more detailed
-Have cord on only one side (more convenient but less reliable over time)
-Have fixed cord (cannot be replaced)
-Have a wider soundstage
-Are less natural sounding
-Are more sibilant/fatiguing. Cymbals sometimes sound harsh.
A few words for those trying to pick between the DT-880 models:
-The Pro and Premium 250 Ohm use the same drivers and therefore sound exactly the same except that the clamp strength is slightly tighter for the Pro than the Premium, which changes the sound a tiny bit (more bass). If you stretch the headband a bit on the Pro, it sounds exactly like the Premium
-The 32 ohm model is meant to be driven by phones, iPods, etc, does not need a dedicated amp, but many who have compared it to the others say that it does not sound as good as the 250 and 600 ohm models
-Most who have done side by side comparisons of the 250 and 600 ohm models find that they sound the same, yet the 600 ohm model has a reputation for being the best sounding, likely because the people using it are pairing it with higher end amps, or possibly just because of "placebo effect". I would and did get the 250 ohm model because it is easier to drive (I can use them without a dedicated amp if I need to, though they sound much better if I do.
-The Pro model comes with a coiled cord, while the Premiums have a straight cord. They also have obvious style differences. I preferred the coiled cord and looks of the Pro model.
The current sub-$200 price of the DT-880 Pro 250 ohm model on Amazon is a steal. They are absolutely at the quality and performance level of my $400 Sennheiser and $300 Hifiman.