OK this can get a bit technical. To get the best out of any speaker tuning is a must. It will come down to a science if you go all out! If its possible front firing sub is best. Add a port and try to glue PVC pipe on the back side of the box. About halfway in the box right behind the sub. This well add to bass and sound stage as well and allow them to breath. jonnywolfet is right try to isolate the mid drivers. If you want them all together put a baffle behind them or if your good a cabinet within a cabinet. You don't want the resonance of the subs to distort the other divers. Some dynamat if you get some rattling. Boom banging speakers! I hope I was of some help.
